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1

A reductive aminase from Aspergillus oryzae

Aleku, Godwin A., France, Scott P., Man, Henry, Mangas-Sanchez, Juan, Montgomery, Sarah L., Sharma, Mahima, Leipold, Friedemann, Hussain, Shahed, Grogan, Gideon, Turner, Nicholas J.

Journal:

Nature Chemistry

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

2

Enzyme‐catalyzed Synthesis of Secondary and Tertiary Amides

Petchey, Mark, Grogan, Gideon

Journal:

Advanced Synthesis & Catalysis

Year:

2019

File:

PDF, 1.85 MB

2019

3

On the biocatalytic cleavage of silicon–oxygen bonds: A substrate structural approach to investigating the cleavage of protecting group silyl ethers by serine-triad hydrolases

Andy Maraite, Marion B. Ansorge-Schumacher, Benjamin Ganchegui, Walter Leitner, Gideon Grogan

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2009

Language:

english

File:

PDF, 242 KB

english, 2009

4

Engineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products

Ghislieri, Diego, Green, Anthony P., Pontini, Marta, Willies, Simon C., Rowles, Ian, Frank, Annika, Grogan, Gideon, Turner, Nicholas J.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 2.74 MB

english, 2013

5

An ( R )-Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines

Hussain, Shahed, Leipold, Friedemann, Man, Henry, Wells, Elizabeth, France, Scott P., Mulholland, Keith R., Grogan, Gideon, Turner, Nicholas J.

Journal:

Year:

2015

Language:

english

File:

PDF, 608 KB

english, 2015

6

NAD(P)H-Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application

Sharma, Mahima, Mangas-Sanchez, Juan, Grogan, Gideon

Journal:

Advanced Synthesis & Catalysis

Year:

2017

Language:

english

File:

PDF, 2.36 MB

english, 2017

7

Biocatalytic conversion of cyclic ketones bearing alpha-quaternary stereocenters to lactones in an enantioselective radical approach to medium-sized carbocycles

Morrill, Charlotte, Jensen, Chantel, Just-Baringo, Xavier, Grogan, Gideon, Turner, Nicholas, Procter, David John

Journal:

Angewandte Chemie International Edition

Year:

2018

Language:

english

File:

PDF, 1.87 MB

english, 2018

8

Biocatalytic conversion of cyclic ketones bearing alpha-quaternary stereocenters to lactones in an enantioselective radical approach to medium-sized carbocycles

Morrill, Charlotte, Jensen, Chantel, Just-Baringo, Xavier, Grogan, Gideon, Turner, Nicholas, Procter, David John

Journal:

Angewandte Chemie

Year:

2018

Language:

english

File:

PDF, 1.87 MB

english, 2018

9

Oxidoreductase-Catalyzed Synthesis of Chiral Amines

Patil, Mahesh D., Grogan, Gideon, Bommarius, Andreas S, Yun, Hyungdon

Journal:

Year:

2018

Language:

english

File:

PDF, 2.68 MB

english, 2018

10

An Asymmetric Enzyme-Catalyzed Retro-Claisen Reaction for the Desymmetrization of Cyclic β-Diketones

Gideon Grogan, Jürgen Graf, Aileen Jones, Simon Parsons, Nicholas J. Turner, Sabine L. Flitsch

Journal:

Angewandte Chemie

Year:

2001

Language:

english

File:

PDF, 91 KB

english, 2001

11

An Asymmetric Enzyme-Catalyzed Retro-Claisen Reaction for the Desymmetrization of Cyclic β-Diketones

Gideon Grogan, Jürgen Graf, Aileen Jones, Simon Parsons, Nicholas J. Turner, Sabine L. Flitsch

Journal:

Angewandte Chemie International Edition

Year:

2001

Language:

english

File:

PDF, 90 KB

english, 2001

12

Desymmetrisations of 1-Alkylbicyclo[3.3.0]octane-2,8-diones by Enzymatic Retro-Claisen Reaction Yield Optically Enriched 2,3-Substituted Cyclopentanones

Cheryl L. Hill, Chandra S. Verma, Gideon Grogan

Journal:

Advanced Synthesis & Catalysis

Year:

2007

Language:

english

File:

PDF, 203 KB

english, 2007

13

On the Resolution of Chiral Substrates by a retro-Claisenase Enzyme: Biotransformations of Heteroannular Bicyclic β-Diketones by 6-Oxocamphor Hydrolase

Cheryl L. Hill, Lee Chiang Hung, Derek J. Smith, Chandra S. Verma, Gideon Grogan

Journal:

Advanced Synthesis & Catalysis

Year:

2007

Language:

english

File:

PDF, 224 KB

english, 2007

14

Edited by Wolf-Dieter Fessner and Thorleif Anthonsen Modern biocatalysis: stereoselective and environmentally friendly reactions Wiley-VCH, 2008, 400 pp £110.00/€132.00 978-3-527-32071-4 (hardcover)

Journal:

Applied Organometallic Chemistry

Year:

2009

Language:

english

File:

PDF, 48 KB

english, 2009

15

Tolerance of β-diketone hydrolases as representatives of the crotonase superfamily towards organic solvents

Elina Siirola, Barbara Grischek, Dorina Clay, Annika Frank, Gideon Grogan, Wolfgang Kroutil

Journal:

Biotechnology and Bioengineering

Year:

2011

Language:

english

File:

PDF, 226 KB

english, 2011

16

Insights into Sequence–Activity Relationships amongst Baeyer–Villiger Monooxygenases as Revealed by the Intragenomic Complement of Enzymes from Rhodococcus jostii RHA1

Claudia Szolkowy, Lindsay D. Eltis, Neil C. Bruce, Gideon Grogan

Journal:

Year:

2009

Language:

english

File:

PDF, 393 KB

english, 2009

17

LICRED: A Versatile Drop-In Vector for Rapid Generation of Redox-Self-Sufficient Cytochrome P450s

Federico Sabbadin, Ralph Hyde, Aelig Robin, Eva-Maria Hilgarth, Marie Delenne, Sabine Flitsch, Nicholas Turner, Gideon Grogan, Neil C. Bruce

Journal:

Year:

2010

Language:

english

File:

PDF, 375 KB

english, 2010

18

ChemInform Abstract: An Asymmetric Enzyme-Catalyzed Retro-Claisen Reaction for the Desymmetrization of Cyclic β-Diketones.

Gideon Grogan, Juergen Graf, Aileen Jones, Simon Parsons, Nicholas J. Turner, Sabine L. Flitsch

Journal:

Year:

2001

File:

PDF, 33 KB

2001

19

Baeyer—Villiger Oxidations

Sabine Flitsch, Gideon Grogan

Journal:

Year:

2003

File:

PDF, 48 KB

2003

20

Oxygenation of C—H and C=C Bonds

Sabine Flitsch, Gideon Grogan, D. Ashcroft

Journal:

Year:

2003

File:

PDF, 49 KB

2003

21

Biohydroxylation Reactions Catalyzed by Enzymes and Whole-Cell Systems

Sabine L. Flitsch, Suzanne J. Aitken, Cathy S.-Y. Chow, Gideon Grogan, Adam Staines

Journal:

Bioorganic Chemistry

Year:

1999

Language:

english

File:

PDF, 266 KB

english, 1999

22

The explosive-degrading cytochrome P450 XplA: Biochemistry, structural features and prospects for bioremediation

Elizabeth L. Rylott, Rosamond G. Jackson, Federico Sabbadin, Helena M.B. Seth-Smith, James Edwards, Chun Shiong Chong, Stuart E. Strand, Gideon Grogan, Neil C. Bruce

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2011

Language:

english

File:

PDF, 567 KB

english, 2011

23

Resolution of fused bicyclic ketones by a recombinant biocatalyst expressing the Baeyer–Villiger monooxygenase gene Rv3049c from Mycobacterium tuberculosis H37Rv

Radka Snajdrova, Gideon Grogan, Marko D. Mihovilovic

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 141 KB

english, 2006

24

Cytochromes P450: exploiting diversity and enabling application as biocatalysts

Journal:

Current Opinion in Chemical Biology

Year:

2011

Language:

english

File:

PDF, 393 KB

english, 2011

25

Biocatalytic esterification of lavandulol in supercritical carbon dioxide using acetic acid as the acyl donor

Teresa Olsen, Francesca Kerton, Ray Marriott, Gideon Grogan

Journal:

Enzyme and Microbial Technology

Year:

2006

Language:

english

File:

PDF, 207 KB

english, 2006

26

Enantioselective oxidations catalyzed by diketocamphane monooxygenase fromPseudomonas putidawith macromolecular NAD in a membrane reactor

Piero Pasta, Giacomo Carrea, Nicoletta Gaggero, Gideon Grogan, Andrew Willetts

Journal:

Biotechnology Letters

Year:

1996

Language:

english

File:

PDF, 288 KB

english, 1996

27

Camphor-grown Pseudomonas putida, a multifunctional biocatalyst for undertaking Baeyer-Villiger monooxygenase-dependent biotransformations

Gideon Grogan, Stanley Roberts, Peter Wan, Andrew Willetts

Journal:

Biotechnology Letters

Year:

1993

Language:

english

File:

PDF, 404 KB

english, 1993

28

Enantioselective oxidations by the diketocamphane monooxygenase isozymes fromPsevdomonas putida

Jean Beecher, Gideon Grogan, Stanley Roberts, Andrew Willetts

Journal:

Biotechnology Letters

Year:

1996

Language:

english

File:

PDF, 412 KB

english, 1996

29

Biotransformation of cycloalkenones; Controlled oxidative and reductive bioconversions byPseudomonas putida

Gideon Grogan, Stanley Roberts, Peter Wan, Andrew Willetts

Journal:

Biotechnology Letters

Year:

1994

Language:

english

File:

PDF, 359 KB

english, 1994

30

Biotransformations by microbial Baeyer-Villiger monooxygenases stereoselective lactone formationin vitroby coupled enzyme systems

Gideon Grogan, Stanley Roberts, Andrew Willetts

Journal:

Biotechnology Letters

Year:

1992

Language:

english

File:

PDF, 357 KB

english, 1992

31

Biotransformation of β-myrcene to geraniol by a strain ofRhodococcus erythropolisisolated by selective enrichment from hop plants

Mark L. Thompson, Ray Marriott, Adam Dowle, Gideon Grogan

Journal:

Applied Microbiology and Biotechnology

Year:

2010

Language:

english

File:

PDF, 231 KB

english, 2010

32

The synthesis of (R)-(+)-lipoic acid using a monooxygenase-catalysed biotransformation as the key step

Brian Adger, M.Teresa Bes, Gideon Grogan, Raymond McCague, Sandrine Pedragosa-Moreau, Stanley M. Roberts, Raffaella Villa, Peter W.H. Wan, Andrew J. Willets

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 986 KB

english, 1997

33

Novel aliphatic epoxide hydrolase activities from dematiaceous fungi

Gideon Grogan, Stanley M. Roberts, Andrew J. Willetts

Journal:

FEMS Microbiology Letters

Year:

1996

Language:

english

File:

PDF, 390 KB

english, 1996

34

Diastereoselective hydroxylation and reduction of derivatised tetrahydrofurans byBeauveria bassiana

Gideon Grogan, John T. Sime, Nicholas J. Turner

Journal:

Biotechnology Letters

Year:

2001

Language:

english

File:

PDF, 70 KB

english, 2001

35

Biotransformations

Journal:

Annual Reports Section "B" (Organic Chemistry)

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

36

Perkin 1 Abstracts: Biocatalysis in Organic Synthesis

Grogan, Gideon, Guilly, Selena, Jackson, Ian, McIntyre, Denise, Carr, Reuben, Flitsch, Sabine, Turner, Nicholas

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2002

Language:

english

File:

PDF, 398 KB

english, 2002

37

A Flavoprotein Monooxygenase that Catalyses a Baeyer–Villiger Reaction and Thioether Oxidation Using NADH as the Nicotinamide Cofactor

Chantel N. Jensen, Dr. Jared Cartwright, Jonathan Ward, Sam Hart, Dr. Johan P. Turkenburg, Sohail T. Ali, Dr. Michael J. Allen, Dr. Gideon Grogan

Journal:

Year:

2012

Language:

english

File:

PDF, 389 KB

english, 2012

38

Intragenomic enzyme complements

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2011

Language:

english

File:

PDF, 662 KB

english, 2011

39

Identification of novel esterases for the synthesis of sterically demanding chiral alcohols by sequence-structure guided genome mining

Giang-Son Nguyen, Mark L. Thompson, Gideon Grogan, Uwe T. Bornscheuer, Robert Kourist

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2011

Language:

english

File:

PDF, 837 KB

english, 2011

40

β-Diketone hydrolases

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2002

Language:

english

File:

PDF, 175 KB

english, 2002

41

Biohydrolysis of substituted styrene oxides by Beauveria densa CMC 3240

Gideon Grogan, Catherine Rippé, Andrew Willetts

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

1997

Language:

english

File:

PDF, 494 KB

english, 1997

42

The biocatalytic reactions of Beauveria spp.

Gideon J Grogan, Herbert L Holland

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2000

Language:

english

File:

PDF, 716 KB

english, 2000

43

Novel aliphatic epoxide hydrolase activities from dematiaceous fungi

Gideon Grogan, Stanley M. Roberts, Andrew J. Willetts

Journal:

FEMS Microbiology Letters

Year:

1996

Language:

english

File:

PDF, 413 KB

english, 1996

44

The Structure of Monoamine Oxidase from Aspergillus niger Provides a Molecular Context for Improvements in Activity Obtained by Directed Evolution

Kate E. Atkin, Renate Reiss, Valentin Koehler, Kevin R. Bailey, Sam Hart, Johan P. Turkenburg, Nicholas J. Turner, A. Marek Brzozowski, Gideon Grogan

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 3.51 MB

english, 2008

45

Oxidation of some prochiral 3-substituted cyclobutanones using monooxygenase enzymes: a single-step method for the synthesis of optically enriched 3-substituted ?-lactones

Gagnon, Ren�, Grogan, Gideon, Groussain, Esther, Pedragosa-Moreau, Sandrine, Richardson, Paul F., Roberts, Stanley M., Willetts, Andrew J., Alphand, V�ronique, Lebreton, Jacques, Furstoss, Roland

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1995

Language:

english

File:

PDF, 301 KB

english, 1995

46

Perkin 1 Abstracts: Biocatalysis in Organic Synthesis

Grogan, Gideon, Guilly, Selena, Jackson, Ian, McIntyre, Denise, Carr, Reuben, Flitsch, Sabine, Turner, Nicholas

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2002

Language:

english

File:

PDF, 483 KB

english, 2002

47

Biotransformations

Journal:

Annual Reports Section "B" (Organic Chemistry)

Year:

2012

Language:

english

File:

PDF, 1.68 MB

english, 2012

48

Ligation independent cloning (LIC) as a rapid route to families of recombinant biocatalysts from sequenced prokaryotic genomes

Bonsor, Daniel, Butz, Stephanie F., Solomons, Julianna, Grant, Stephanie, Fairlamb, Ian J. S., Fogg, Mark J., Grogan, Gideon

Journal:

Organic & Biomolecular Chemistry

Year:

2006

Language:

english

File:

PDF, 299 KB

english, 2006

49

A Gene-Fusion Approach to Enabling Plant Cytochromes P450 for Biocatalysis

Schückel, Julia, Rylott, Elizabeth L., Grogan, Gideon, Bruce, Neil C.

Journal:

Year:

2012

Language:

english

File:

PDF, 643 KB

english, 2012

50

Cloning, expression, characterisation and mutational analysis of l-aspartate oxidase from Pseudomonas putida

Leese, Charlotte, Fotheringham, Ian, Escalettes, Franck, Speight, Robert, Grogan, Gideon

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2013

Language:

english

File:

PDF, 479 KB

english, 2013